The FGFR3monitor is a real-time PCR kit for the qualitative detection of four hotspot mutations in the FGFR3 gene [exon 7: p.R248C (c.742C>T) and p.S249C (c.746C>G) and exon 10: p.G372C (c.1114G>T) and p.Y375C (c.1124A>G)] in DNA samples derived from frozen/FFPE tumor tissues or urothelial tumor cells found in urine.
FGFR3 mutations have been implicated in various cancers, including bladder cancer, cervical cancer, and multiple myeloma. FGFR3monitor is indicated for use as an aid in identifying patients harbouring these mutations, particularly to stratify patients for treatment with FGFR3 inhibitors as well as to monitor those under surveillance for non-muscle invasive bladder cancer (NMIBC) recurrence.
FGFR3 mutations have been implicated in various cancers, including bladder cancer, cervical cancer, and multiple myeloma. FGFR3monitor is indicated for use as an aid in identifying patients harbouring these mutations, particularly to stratify patients for treatment with FGFR3 inhibitors as well as to monitor those under surveillance for non-muscle invasive bladder cancer (NMIBC) recurrence.
Material Safety Datasheet (MSDS) - FGFR3monitor_MSDS-FGFR3m-001-V1.1.pdf
User Handling Guide - FGFR3monitor_Handling Guide.pdf